South Italy Travel Itinerary: Best Routes, Hidden Gems, and Tips

Sep 8 2025
South Italy Travel Itinerary: Best Routes, Hidden Gems, and Tips

Southern Italy offers a perfect mix of rich history, stunning beaches, and delicious food. This Southern Italy itinerary takes you on a journey through picturesque beaches and charming little towns, covering the best destinations from the Amalfi Coast to Sicily and Puglia. Whether you’re on a Southern Italy road trip or a shorter visit, this guide provides essential tips and flexible options, including a two-week and one-week itinerary. From relaxing beach days and ancient ruins to exploring historic centres, this itinerary caters to all types of travelers.

Introduction to Southern Italy

Southern Italy is a treasure trove of rich history, stunning landscapes, and delicious cuisine, offering an authentic Italian experience. Home to iconic destinations like the Amalfi Coast, the sun-kissed shores of Puglia, and the vibrant island of Sicily, this region is perfect for exploring picturesque beaches, charming towns, and cultural sites. Whether you’re visiting for a few days or weeks, every stop promises a unique blend of tradition, beauty, and history, making Southern Italy a must-visit destination.

Best Time to Visit Southern Italy

The best time to visit Southern Italy is during the shoulder seasons, late spring (April to June) and early fall (September to October). These months offer mild temperatures, fewer crowds, and the chance to explore picturesque beaches along the Amalfi Coast or Sicily. Itโ€™s also ideal for Southern Italy road trips, visiting historic old towns like Naples, and enjoying day trips to nearby attractions. Summer brings peak season crowds and higher prices, while winter (November to March) is perfect for cultural exploration with fewer tourists and milder temperatures.

When is the Best Time to Visit Southern Italy?

The best time to visit Southern Italy is during the shoulder seasons, specifically late spring (April to June) and early fall (September to October). Early October is particularly ideal for mild weather and fewer tourists. These months offer ideal weather and fewer crowds, making them perfect for a road trip along the stunning Amalfi Coast or enjoying the Adriatic Sea. This is also a great time for day trips to nearby towns and attractions.

Visiting during the peak season (July and August) will bring more tourists, higher prices, and warmer temperatures, especially in Sicily and along the Mediterranean Sea. The crowds can make visiting the historic old towns and famous coastal spots more challenging, so plan your Southern Italy trip accordingly.

Getting to Southern Italy

Reaching Southern Italy is easy, with major airports in Naples, Bari, and Catania offering direct flights from many European cities and beyond. For those already in Italy, high-speed trains and buses connect the north to the south, making it simple to start your Southern Italy road trip from almost anywhere. However, renting a car is recommended for the most flexibility, allowing you to explore at your own pace, discover hidden gems, and visit smaller towns. If you prefer public transport, check schedules in advance, as some rural routes are less frequent. Planning ensures a smooth journey through Southern Italy.

Day-by-Day Southern Italy Travel Itinerary

This Southern Italy road trip itinerary is designed for a two-week journey but can be easily adapted for shorter or longer stays. Starting in Naples, explore the historic old town and the National Archaeological Museum, then visit Pompeii and Mount Vesuvius. Drive along the stunning Amalfi Coast, stopping in Positano and Ravello, then head to Puglia to see Materaโ€™s cave dwellings and Alberobelloโ€™s trulli houses. Next, fly to Sicily to explore Catania and enjoy Palermoโ€™s street food scene. Spend Day 9 uncovering hidden gems like Castelmezzano and Grotte di Frasassi before finishing in San Vito Lo Capo or returning to Naples. If starting or ending in Rome, the Eternal City offers a perfect gateway. This itinerary offers a perfect blend of rich history, picturesque beaches, and delicious food, making it a great way to explore Southern Italy.

Day 1: Arrival in Naples & Explore the City

Start your journey in Naples, a city with a rich history and delicious food. The main train station is conveniently located near the town centre, making it easy to access the city’s main attractions. Many of Naples’ highlights are within walking distance of each other, allowing you to explore with ease. Begin your day by exploring the historic centre and visiting the National Archaeological Museum, home to ancient treasures from Pompeii. Take a short walk to Spaccanapoli, one of Naplesโ€™ narrowest streets, where you can indulge in the world-famous pizza margherita.

Top Activities:

  • Discover the historic old town of Naples, which is a UNESCO World Heritage site.
  • Visit the Royal Palace of Naples and explore the nearby city walls.

Day 2: Pompeii & Mount Vesuvius

No visit to Southern Italy would be complete without a trip to Pompeii, the ancient Roman city destroyed by the eruption of Mount Vesuvius in 79 AD. The drive from Naples to Pompeii takes about an hour, making it a quick and easy journey by car, while public transport options can be more time-consuming. Youโ€™ll spend the morning exploring the ruins of Pompeii before heading to Mount Vesuvius for a hike to the summit, which offers breathtaking views of the surrounding area. The journey from Pompeii to Mount Vesuvius takes a little over half an hour by car.

Activities:

  • Walk through Pompeiiโ€™s ancient ruins and learn about life before the eruption. Entry tickets can be purchased at the ticket office, or you can buy your ticket online in advance.
  • Climb Mount Etna for stunning views of Naples and the Bay of Naples.

Day 3-4: Amalfi Coast & Positano

Drive along the spectacular Amalfi Coast, famous for its dramatic cliffs and colorful white-washed buildings. Your first stop should be Positano, a lovely town nestled between the cliffs and the sea. Itโ€™s the perfect base for exploring the coast. If youโ€™re driving, look for accommodations or attractions that offer free parking to make your stay more convenient and budget-friendly.

There are a few options for getting around the coast, including ferries, buses, and private tours, giving you flexibility to explore at your own pace.

Top Stops:

  • Enjoy a boat trip along the coastline, soaking in views of picturesque beaches and coastal villages. Consider taking a boat tour to the Blue Grotto, a must-see sea cave near Capri that is famous for its stunning blue waters.
  • Take a half-day trip to Ravello and visit Villa Rufolo, known for its beautiful gardens and incredible views.

Day 5-6: Puglia – Matera and Alberobello

Next, head to Puglia, located in Italy’s heel, starting with Matera, where youโ€™ll find ancient Sassi cave dwellings that date back thousands of years. There are only a couple of main roads connecting Matera and Alberobello, making navigation simple. Then head to Alberobello, home to the famous trulli houses, which are traditional olive groves and stone buildings with conical roofs. For a unique side trip, consider visiting Gravina in Puglia to see its iconic bridge featured in a James Bond film.

Highlights:

  • Explore Materaโ€™s ancient ruins and walk through its famous Sassi cave dwellings.
  • Visit Alberobello, a historic building filled with charming trulli houses.

Day 7-8: Sicily – Catania and Palermo

Fly to Sicily to explore Catania and Palermo. In Catania, marvel at the historic centre, with its baroque buildings and stunning views of Mount Etna. In Palermo, youโ€™ll find a vibrant historic centre filled with street food markets, delicious local cuisine, and plenty of wine tasting opportunities. Both cities’ historic centres are must-see attractions for anyone interested in Sicily’s rich culture and history. This section can also serve as a standalone Sicily itinerary for travelers focusing on the island. Consider taking day trips to the charming small towns near Palermo or Catania to experience authentic local life.

Top Activities:

  • Visit Mount Etna and take a boat tour around the coast.
  • Explore Palermo Cathedral and the Ballarรฒ Market for a taste of local life.

Day 9: Hidden Gems of Southern Italy

Southern Italy is filled with hidden gems that many travelers overlook. Many of these are small towns where attractions, restaurants, and local shops are often within walking distance, making it easy to explore on foot. Discover the lovely town of Castelmezzano, a village nestled between cliffs in the Lucanian Dolomites, and the Grotte di Frasassi, one of Europeโ€™s largest and most stunning cave systems.

Top Stops:

  • Visit Castelmezzano, a charming little town offering incredible views and a half-day trip to hike the famous Volo dellโ€™Angelo zip line. Most sights and amenities are within walking distance in the village.
  • Explore Grotte di Frasassi, one of the most impressive natural wonders in Italy.

Tip: When visiting these lesser-known destinations, look for free parking options nearby to save money and enjoy convenient access to the attractions.

Day 10: Departure from Sicily or Return to Naples

Conclude your journey by reaching your final destination, either San Vito Lo Capo or Naples. If youโ€™re departing from Palermo or taking a ferry back to Naples, remember to purchase your ferry or train tickets at the ticket office before departure. If you return to Naples by train, the train station offers convenient access to the city center and nearby accommodations. If youโ€™re still in Sicily, enjoy a short walk around San Vito Lo Capo, a port town known for its sandy beaches and stunning coastal views.

Highlights:

  • Spend your last morning enjoying the beach at San Vito Lo Capo, your final destination in Sicily.
  • Return to Naples and explore the city center before your flight, with easy access from the train station.

Calabria Region Highlights

Calabria, a hidden gem in Southern Italy, offers stunning beaches and rich history. Nestled between the Tyrrhenian and Ionian Seas, it features the charming town of Tropea with dramatic cliffs and a historic centre, as well as the picturesque fishing village of Scilla. Nature lovers will enjoy Calabriaโ€™s national parks, ideal for hiking. Adding Calabria to your Southern Italy itinerary offers an off-the-beaten-path experience, combining natural beauty and ancient history.

Essential Travel Tips for Southern Italy

  • Getting Around: Renting a car is essential for exploring Southern Italy. Many areas, such as Positano and Matera, are best reached by car, and having a rental car gives you flexibility to visit more remote destinations like Castelmezzano and Grotte di Frasassi. For transportation, there are a few options for getting between destinations, such as a car, train, or bus. However, keep in mind that public transport can be time-consuming compared to driving, especially when reaching smaller towns.
  • Italian Driving Tips: When driving in Italy, be aware of local rules and customs. Italian driving often involves frequent horn usage, awareness of speed cameras, and navigating motorway tolls. Understanding these customs and preparing accordingly will help you drive safely and confidently.
  • What to Pack: Comfortable walking shoes are a must, as well as sunscreen, a camera, and light layers for the evenings. Be sure to have travel insurance in case of any changes to your plans.

What to Pack for Southern Italy

For your Southern Italy road trip, pack lightweight clothing, comfortable walking shoes, and sun protection for hot summers, or layers and a light jacket for cooler months. Sturdy hiking boots are essential for outdoor activities. Donโ€™t forget a power adapter, as Italy uses different plugs. If you’re visiting beaches or taking boat tours, pack swimwear and a quick-dry towel. Proper packing ensures you’re ready for every adventure Southern Italy offers.

Accommodation in Southern Italy

Southern Italy offers a wide range of accommodations for all budgets and preferences, from charming B&Bs and boutique hotels in historic towns to luxurious villas with sea views. Popular spots like Positano, Amalfi, and Ravello are ideal for exploring the Amalfi Coast, while agriturismos offer peaceful stays surrounded by olive groves and vineyards. For something unique, consider a traditional trullo in Puglia or a historic building. During peak season, accommodations fill up quickly, so book early to secure your spot. Whether itโ€™s a cozy guesthouse or a lavish resort, Southern Italy promises an unforgettable stay.

Conclusion

In conclusion, Southern Italy offers an unforgettable blend of history, culture, and natural beauty, making it a perfect destination for any traveler. Whether you’re exploring ancient ruins, relaxing on picturesque beaches, or enjoying delicious food, this region provides something for everyone. From the iconic Amalfi Coast to the hidden gems of Sicily and Puglia, the journey through Southern Italy promises both adventure and relaxation. With careful planning and the right itinerary, your Southern Italy road trip will be an experience you’ll cherish for years to come.

Ready to experience the charm of Southern Italy like never before? At True Colors of Italy, we offer private, all-inclusive day tours that immerse you in the rich culture, stunning landscapes, and delicious cuisine of this beautiful region. Whether you’re traveling solo or with a small group, our curated experiences are designed for those who seek authenticity, comfort, and local insight. Contact us today to start planning your personalized Southern Italy adventure!

FAQs

What is the best time to visit Southern Italy?

The best time to visit Southern Italy is during the shoulder seasons, late spring (April to June) and early fall (September to October). These seasons offer mild temperatures and fewer crowds, making them ideal for exploring the coast and historic old towns.

How should I get around Southern Italy?

Renting a car is the best way to explore Southern Italy. It allows you to reach more remote towns, such as Matera and Positano, and enjoy flexibility when exploring smaller towns.

What are the must-try foods in Southern Italy?

Southern Italy is renowned for its Mediterranean cuisine. Donโ€™t miss out on pizza margherita in Naples, pasta alla Norma in Sicily, and fresh seafood along the Mediterranean Sea. Enjoy local wine at vineyards and during wine tasting experiences.

What are the must-see hidden gems in Southern Italy?

Southern Italy is full of hidden gems such as Castelmezzano, a lovely town with stunning views, and Grotte di Frasassi, one of Italyโ€™s largest and most beautiful cave systems. These locations are less crowded, offering an authentic experience of Southern Italy.

 

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